Medullary carcinoma is a rare breast carcinoma with a syncytial growth pattern and high-grade cytology. It can be difficult to diagnose and may be missed on conventional imaging as the findings may overlap with benign lesions i. The authors report a case of a year-old female who presented with multifocal breast lumps diagnosed with medullary carcinoma and fibroadenomas. Imaging and pathological correlation with contrast-enhanced MRI are presented in the diagnosis of these lesions. Medullary carcinoma of the breast is a rare subtype of invasive breast carcinoma with a high-grade cytology but has been reported to have a good prognosis. It is also more common in women who have a BRCA1 mutation.
What does "enhancement" mean on MRI? - Neurofibromatosis
MRI and Medical Imaging: Magnetic Resonance Imaging of the Breast
Some benign pathologic entities of the breast, when diagnosed at image-guided core needle biopsies, have the potential to be upgraded to invasive carcinoma or ductal carcinoma in situ DCIS upon complete excision by surgery. These entities are collectively categorized as high-risk lesions and include atypical ductal hyperplasia ADH , flat epithelial atypia FEA , atypical lobular hyperplasia ALH , lobular carcinoma in situ LCIS , papillary lesions, radial scar, phyllodes tumor, and mucocele-like lesions. This chapter describes magnetic resonance imaging MRI features of these lesions. ADH defines a group of epithelial proliferative lesions that have some, but not all, of the features of DCIS, either by lack of a major defining cytologic feature of carcinoma or by having the features to a lesser extent than true DCIS i.
Magnetic resonance imaging MRI of the breast was first performed in the late s. At first, differentiation between benign and malignant breast lesions was primarily based on their differences in T1 and T2 relaxations times Rausch et al. Due to the large overlap in T1 and T2 relaxation times in benign and malignant breast lesions, it became apparent that contrast administration was mandatory for reliable breast MRI.
My daughter Katie is 2 and has a growing optic glioma impacting the chiasm. Her latest MRI indicates some "enhancement" in the chiasm. I know this is not good - but am a little unsure as to what this means. Does it mean the tumor is gaining mass or getting thicker? If anyone has experience with enhancement in the chiasm - what did this mean for you?